Technologies

Sequence profiling of the immune repertories.”

Our technologies are designed and engineered to comprehensively and efficiently profile the human immune repertoire at the sequence level.

 

Next Generation Sequencing

 

  • Starts with human peripheral blood
  • Amplifies immunoglobulin variable regions from IgG, IgK, IgL, IgM, and IgA
  • Tolerates extensive sequence changes caused by somatic hyper mutation and affinity maturation

Bioinformatics

 

  • Assembles full-length variable regions
  • Annotates FR and CDR regions
  • Distinguishes IgG subtypes (IgG1, IgG2, IgG3, and IgG4)
  • Tabulates clone and mutation frequency

Synthetic Biology

 

  • Optimized expression construction via high-throughput gene synthesis
  • Rapid turn-around time
  • Cost-effective

High-Throughput Antibody Expression

 

  • Transient mammalian expression system
  • 96-well plate format
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